Search results for "Fdg uptake"

showing 3 items of 3 documents

Influence of cell proportions and proliferation rates on FDG uptake in squamous-cell esophageal carcinoma: a PET study.

2008

We investigated the influence of cell proportions and proliferation activities on tumor maximum standard uptake value (SUV(max)) in patients with squamous-cell esophageal cancer (SCEC).Sixteen (16) patients with untreated SCEC were examined with (18)F-flourodeoxyglucose positron emission tomography (FDG-PET). The tumor SUV(max) were calculated. Tumors were resected by transthoracic esophagectomy. Tissues were stained with hematoxylin and eosin for the measurement of cell proportions and MIB-1 for measurement of proliferation indices (PIs). Tumor SUV and histologic data were related by using multiple linear regression analysis.The mean proportion of tumor cells in the tumor site was 58.1% (+…

MaleCancer ResearchPathologymedicine.medical_specialtyEsophageal NeoplasmsCellH&E stainStandardized uptake valueFluorodeoxyglucose F18medicineCarcinomaHumansRadiology Nuclear Medicine and imagingAgedCell ProliferationCell SizePharmacologymedicine.diagnostic_testbusiness.industryFdg uptakeGeneral MedicineEsophageal cancerMiddle Agedmedicine.diseaseImmunohistochemistrymedicine.anatomical_structureOncologyPositron emission tomographyPositron-Emission TomographyCarcinoma Squamous CellMultiple linear regression analysisFemalebusinessCancer biotherapyradiopharmaceuticals
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[18F]FDG-PET predicts complete pathological response of breast cancer to neoadjuvant chemotherapy

2007

To evaluate, in breast cancer patients treated by neoadjuvant chemotherapy, the predictive value of reduction in FDG uptake with regard to complete pathological response (pCR).Forty-seven women with non-metastatic, non-inflammatory, large or locally advanced breast cancer were included. Tumour uptake of FDG was evaluated before and after the first course of neoadjuvant chemotherapy. Four indices were used: maximal and average SUV without or with correction by body surface area and glycaemia (SUV(max), SUV(avg), SUV(max-BSA-G) and SUV(avg-BSA-G), respectively). The predictive value of reduction in FDG uptake with respect to pCR was studied by logistic regression analysis. Relationships betwe…

Oncologymedicine.medical_specialtymedicine.medical_treatmentPathological responseAntineoplastic AgentsBreast Neoplasms[SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicineSensitivity and Specificity030218 nuclear medicine & medical imaging18f fdg pet[SDV.IB.MN] Life Sciences [q-bio]/Bioengineering/Nuclear medicine[ SDV.IB.MN ] Life Sciences [q-bio]/Bioengineering/Nuclear medicine03 medical and health sciences0302 clinical medicineBreast cancerFluorodeoxyglucose F18Internal medicinemedicineHumansRadiology Nuclear Medicine and imagingNeoadjuvant therapyComputingMilieux_MISCELLANEOUSChemotherapymedicine.diagnostic_testbusiness.industryFdg uptakeReproducibility of ResultsGeneral MedicineMiddle Agedmedicine.diseasePrognosisNeoadjuvant Therapy3. Good healthClinical trialTreatment OutcomePositron emission tomography030220 oncology & carcinogenesisPositron-Emission TomographyFemaleRadiopharmaceuticalsbusiness
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Environmental Tobacco Smoke During the Early Postnatal Period of Mice Interferes With Brain 18 F-FDG Uptake From Infancy to Early Adulthood – A Longi…

2020

Exposure to environmental tobacco smoke (ETS) is associated with high morbidity and mortality, mainly in childhood. Our aim was to evaluate the effects of postnatal ETS exposure in the brain 2-deoxy-2-[18F]-fluoro-D-glucose (18F-FDG) uptake of mice by positron emission tomography (PET) neuroimaging in a longitudinal study. C57BL/6J mice were exposed to ETS that was generated from 3R4F cigarettes from postnatal day 3 (P3) to P14. PET analyses were performed in male and female mice during infancy (P15), adolescence (P35), and adulthood (P65). We observed that ETS exposure decreased 18F-FDG uptake in the whole brain, both left and right hemispheres, and frontal cortex in both male and female i…

0301 basic medicineCingulate cortexmedicine.medical_specialtyCerebellumpositron emission tomographyglucose metabolismbrainThalamusHippocampusenvironmental tobacco smokeStriatum18F-FDG uptakelcsh:RC321-571Midbrain03 medical and health sciences0302 clinical medicineInternal medicineCortex (anatomy)medicinelcsh:Neurosciences. Biological psychiatry. NeuropsychiatryOriginal ResearchBasal forebrainpassive smokeneuroimagingbusiness.industryGeneral Neurosciencelongitudinal studyCÉREBRO030104 developmental biologyEndocrinologymedicine.anatomical_structurebusiness030217 neurology & neurosurgeryNeuroscienceFrontiers in Neuroscience
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